Vesicle Priming and Depriming A SNAP Decision

نویسندگان

  • Ruth Heidelberger
  • Gary Matthews
چکیده

Synapses have a limited pool of vesicles that are docked and primed for rapid release. In neuroendocrine cells, splice variants of the SNARE protein SNAP-25 and phosphorylation of SNAP-25 independently influence the size of the releasable vesicle pool, possibly by altering the rate of vesicle depriming. Pre- and posttranslational modifications of SNAP-25 may therefore affect synaptic strength.

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عنوان ژورنال:
  • Neuron

دوره 41  شماره 

صفحات  -

تاریخ انتشار 2004